Arqule Inc Watch

from 8-K 37 pages Arqule, Inc. (A Delaware Corporation) 9,250,000 Shares of Common Stock Underwriting Agreement

from 8-K 37 pages Arqule, Inc. (A Delaware Corporation) 11,000,000 Shares of Common Stock Underwriting Agreement

from 8-K 40 pages Arqule, Inc. Common Stock ($0.01 Par Value Per Share) Capital on Demand™ Sales Agreement

from 8-K 21 pages Securities Purchase Agreement

from 8-K 27 pages Arqule, Inc. (A Delaware Corporation) 7,150,000 Shares of Common Stock Underwriting Agreement

from 8-K 26 pages Arqule, Inc. (A Delaware Corporation) 7,000,000 Shares of Common Stock Underwriting Agreement

from 8-K 51 pages Arqule, Inc. 7,000,000 Shares Common Stock ($0.01 Par Value Per Share) Underwriting Agreement

from SC 13G/A 1 page Exhibit 1.1 Joint Filing Agreement the Undersigned Hereby Agree That the Statement on This Schedule 13g/A, Dated September 24, 2003, (The "Schedule 13g/A"), With Respect to the Common Stock, Par Value $.01 Per Share, of Arqule, Inc. Is Filed on Behalf of Each of US Pursuant to and in Accordance With the Provisions of Rule 13d-1(k) Under the Securities and Exchange Act of 1934, as Amended, and That This Agreement Shall Be Included as an Exhibit to This Schedule 13g/A. Each of the Undersigned Agrees to Be Responsible for the Timely Filing of the Schedule 13g/A, and for the Completeness and Accuracy of the Information Concerning Itself Contained Therein. This Agreement May Be Executed in Any Number of Counterparts, All of Which Taken Together Shall Constitute One and the Same Instrument. in Witness Whereof, the Undersigned Have Executed This Agreement as of the 24th Day of September, 2003. Orbimed Advisors LLC By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Title: Managing Member Orbimed Capital LLC By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Title: Managing Member By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Pw Alternative Asset Management, Inc. By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Title: Vice President Ubs Eucalyptus Management, L.L.C. by Ubs Fund Advisor, L.L.C. Its Managing Member By: /S/ Michael Mascis Name: Michael Mascis Title: Vice President of Pw Alternative Asset Management, Inc

from SC 13G/A 1 page Exhibit 1.1 Joint Filing Agreement the Undersigned Hereby Agree That the Statement on This Schedule 13g/A, Dated September 24, 2003, (The "Schedule 13g/A"), With Respect to the Common Stock, Par Value $.01 Per Share, of Arqule, Inc. Is Filed on Behalf of Each of US Pursuant to and in Accordance With the Provisions of Rule 13d-1(k) Under the Securities and Exchange Act of 1934, as Amended, and That This Agreement Shall Be Included as an Exhibit to This Schedule 13g/A. Each of the Undersigned Agrees to Be Responsible for the Timely Filing of the Schedule 13g/A, and for the Completeness and Accuracy of the Information Concerning Itself Contained Therein. This Agreement May Be Executed in Any Number of Counterparts, All of Which Taken Together Shall Constitute One and the Same Instrument. in Witness Whereof, the Undersigned Have Executed This Agreement as of the 24th Day of September, 2003. Orbimed Advisors LLC By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Title: Managing Member Orbimed Capital LLC By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Title: Managing Member By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Pw Alternative Asset Management, Inc. By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Title: Vice President Ubs Eucalyptus Management, L.L.C. by Ubs Fund Advisor, L.L.C. Its Managing Member By: /S/ Michael Mascis Name: Michael Mascis Title: Vice President of Pw Alternative Asset Management, Inc

from SC 13G/A 1 page Agreement Regarding Joint Filing

from SC 13G/A 1 page Exhibit 1.1 Joint Filing Agreement the Undersigned Hereby Agree That the Statement on Schedule 13g/A, Dated February 14, 2003, (The "Schedule 13g/A"), With Respect to the Common Stock, $.01 Par Value, of Arqule, Inc. Is Filed on Behalf of Each of US Pursuant to and in Accordance With the Provisions of Rule 13d-1(k) Under the Securities and Exchange Act of 1934, as Amended, and That This Agreement Shall Be Included as an Exhibit to This Schedule 13g/A. Each of the Undersigned Agrees to Be Responsible for the Timely Filing of the Schedule 13g/A, and for the Completeness and Accuracy of the Information Concerning Itself Contained Therein. This Agreement May Be Executed in Any Number of Counterparts, All of Which Taken Together Shall Constitute One and the Same Instrument. in Witness Whereof, the Undersigned Have Executed This Agreement as of the 14th Day of Febraury, 2003. Orbimed Advisors Inc. By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Title: President Orbimed Advisors LLC By: /S/ Samuel D. Isaly Name: Samuel D. Isaly Title: President of Managing Member, Orbimed Advisors Inc. By: /S/ Samuel D. Isaly Name: Samuel D. Isaly

from SC 13G 1 page Agreement Regarding Joint Filing

from S-3/A ~20 pages Form of Underwriting Agreement

from SC 13G/A 1 page Exhibit 1 This Document Has Been Signed in Counterpart Joint Filing Agreement in Accordance With Rule 13d-1(f) Under the Securities Exchange Act of 1934, the Persons Named Below Agree to the Joint Filing on Behalf of Each of Them of a Statement on Schedule 13g (Including Amendments Thereto) With Respect to the Common Stock of Arqule, Inc., and Further Agree That This Joint Filing Agreement Be Included as an Exhibit to Such Joint Filings. in Evidence Thereof Each of the Undersigned, Being Duly Authorized, Hereby Execute This Agreement on the Date Set Forth Opposite Its or His Name. Sevin Rosen Fund IV L.P. By: Srb Associates IV L.P., General Partner Dated: February 13, 1998 By:/S/ John Jaggers John V. Jaggers, a General Partner Srb Associates IV L.P. Dated: February 13, 1998 By:/S/ John Jaggers John V. Jaggers, a General Partner Dated: February 13, 1998 /S/ Jon W. Bayless Jon W. Bayless Dated: February 13, 1998 /S/ John Jaggers, Attorney-In-Fact Stephen M. Dow Dated: February 13, 1998 /S/ John Jaggers John V. Jaggers Dated: February 13, 1998 /S/ John Jaggers, Attorney-In-Fact Charles H. Phipps Page 1 of 1

from S-1/A ~50 pages Form of Underwriting Agreement

from S-1 ~20 pages Form of Underwriting Agreement

from S-1/A ~20 pages Form of Underwriting Agreement

from S-1 ~20 pages Underwriting Agreement