EPIX Pharmaceuticals, Inc. Watch

from 8-K 5 pages Note Purchase Agreement

from 8-K 7 pages Exchange Agreement

from 8-K 14 pages Contingent Value Rights Agreement

from 8-K 13 pages Employment Agreement

from 8-K 12 pages Termination Agreement

from SC TO-C 12 pages Termination Agreement

from SC TO-C 51 pages Asset Purchase Agreement as of April 6, 2009

from 8-K 51 pages Asset Purchase Agreement as of April 6, 2009

from 10-K 23 pages Confidential Treatment

from 8-K 2 pages Via Electronic Delivery March 9, 2009 Glaxosmithkline 2301 Renaissance Boulevard Mail Code Rn0210 King of Prussia, Pa 19406 Attn.: Vice President, Business Development Center of Excellence for External Drug Development Glaxosmithkline Greenford Road Greenford, Middlesex Ub6 Ohe Attn.: Vice President, Transactions Worldwide Business Development Re: Development and License Agreement Among Smithkline Beecham Corporation, Doing Business as Glaxosmithkline, Glaxo Group Limited (Collectively “Gsk”) and EPIX Pharmaceuticals, Inc. (“Epix”) Dated December 11, 2006 (The “Agreement”) Dear Sir or Madam: Reference Is Made Hereby to the Agreement. Capitalized Terms Used but Not Defined Herein Shall Have the Meaning Provided in the Agreement

from 8-K 4 pages Amendment to Employment Agreement

from 8-K 15 pages Employment Agreement

from 10-Q >50 pages Ex-10.6 Lease, as Amended Through June 2, 2008

from 8-K 12 pages Registration Rights Agreement

from 8-K 39 pages Common Stock Purchase Agreement by and Between Kingsbridge Capital Limited and EPIX Pharmaceuticals, Inc. Dated as of August 4, 2008

from 8-K 4 pages I Am Pleased to Offer You, Subject to the Terms of This Letter Agreement (This “Letter Agreement”), the Position of Interim Chief Executive Officer of EPIX Pharmaceuticals, Inc. (The “Company”) for a Start Date of July 28, 2008. Except as Expressly Provided Herein, This Letter Agreement Shall Fully Supersede All Previous Agreements, Arrangements or Understandings Between You and the Company, Including, but Not Limited To, the Service Agreement Between the Company and Energetics, LLC (The “Service Agreement”; Provided That Section 5 of the Service Agreement Shall Remain in Full Force and Effect. 1. Position You Will Serve as Interim Chief Executive Officer of the Company and Will Report Directly to the Company’s Board of Directors. 2. Extent of Service

from 8-K 8 pages Separation Agreement

from 8-K 9 pages Employment Agreement

from 8-K 17 pages Separation Agreement and Post-Employment Consulting Agreement

from 8-K 28 pages EPIX Pharmaceuticals, Inc. 2008 Stock Option and Incentive Plan