Annovis Bio Inc. Watch

from 10-K 6 pages Description of Registrant’s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934

from S-3 51 pages Annovis Bio, Inc., Issuer and [Trustee], Trustee Indenture Dated as of , 20__ Debt Securities I

from 10-K 5 pages Description of Registrant’s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934

from 10-K 16 pages Warrant to Purchase Common Stock Annovis Bio, Inc

from S-1/A 2 pages Ab Annovis Bio, Inc. See Reverse for Certain Definitions Cusip 03615a 10 8 Incorporated Under the Laws of the State of Delaware This Certifies That Is the Record Holder of Fully Paid and Non-Assessable Shares of Common Stock, $0.0001 Par Value Per Share, of Annovis Bio, Inc. Transferable on the Books of the Corporation in Person or by Duly Authorized Attorney Upon Surrender of the Certificate Properly Endorsed. This Certificate Is Not Valid Until Countersigned by the Transfer Agent and Registered by the Registrar. Witness the Facsimile Seal of the Corporation and the Facsimile Signatures of Its Duly Authorized Officers. Dated: Seal 2008 President and Chief Executive Officer Secretary, Treasurer and Chief Financial Officer • Countersigned and Registered: American Stock Transfer & Trust Company, LLC (Brooklyn, Ny) Transfer Agent and Registrar By: Authorized Signature