Pfenex Inc. Watch

from 10-K 4 pages Description of the Registrant’s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934

from S-3 75 pages Pfenex Inc. to as Trustee Indenture Dated as of , 20 Subordinated Debt Securities

from S-3 60 pages Pfenex Inc. to as Trustee Indenture Dated as of , 20 Senior Debt Securities

from S-3 75 pages Pfenex Inc. to as Trustee Indenture Dated as of , 20 Subordinated Debt Securities

from S-3 66 pages Pfenex Inc. to as Trustee Indenture Dated as of , 20 Senior Debt Securities

from S-1/A 30 pages Pfenex Inc. Investors’ Rights Agreement

from S-1/A 2 pages See Reverse for Certain Definitions Delaware This Certifies That Is the Record Holder of Fully Paid and Nonassessable Shares of Common Stock, $0,001 Par Value, of Pfenex Inc. Transferable on the Books of the Corporation in Person or by Duly Authorized Attorney Upon Surrender of This Certificate Properly Endorsed. This Certificate Is Not Valid Until Countersigned by the Transfer Agent and Registered by the Registrar. Witness the Facsimile Seal of the Corporation and the Facsimile Signatures of Its Duly Authorized Officers. Dated: # % President & Chief Executive Officer S / Geal \ = Secretary

from S-1 10 pages Amended and Restated Subscription Agreement

from S-1 27 pages Pfenex Inc. Investors’ Rights Agreement

from DRS 10 pages Amended and Restated Subscription Agreement

from DRS 27 pages Pfenex Inc. Investors’ Rights Agreement

from DRS 30 pages Amended and Restated Bylaws of Pfenex, Inc