21st Century Oncology Holdings, Inc. Watch

from 8-K 44 pages Third Supplemental Indenture

from 8-K 12 pages Second Supplemental Indenture

from 10-Q 5 pages First Supplemental Indenture

from 8-K 15 pages 21st Century Oncology Holdings, Inc. 10% Subordinated Unsecured Pik Notes Due 2019

from 8-K 10 pages Third Supplemental Indenture

from 8-K 128 pages 21st Century Oncology, Inc. and Wilmington Trust, National Association, as Trustee 11.00% Senior Notes Due 2023 Indenture Dated as of April 30, 2015

from 10-K 9 pages Second Supplemental Indenture

from 10-K 9 pages First Supplemental Indenture

from 10-K 9 pages Second Supplemental Indenture

from 10-K 9 pages Tenth Supplemental Indenture

from S-1/A 27 pages Certificate of Designation of [ ]% Series a Mandatory Convertible Junior Non-Voting Preferred Stock of 21st Century Oncology Holdings, Inc

from S-1/A 27 pages Certificate of Designation of [ ]% Series a Mandatory Convertible Junior Non-Voting Preferred Stock of 21st Century Oncology Holdings, Inc

from S-1/A 1 page ICC Incorporated Under the Laws of the State of Delaware Common Stock See Reverse for Certain Definitions Cusip 85172j 10 1 This Certifies That Is the Record Holder of Fully Paid and Non-Assessable Shares of Common Stock, $0.0001 Par Value, of 21st Century Oncology Holdings, Inc. Transferable Only on the Books of the Corporation in Person or by Duly Authorized Attorney, Upon Surrender of This Certificate Properly Endorsed. This Certificate Is Not Valid Unless Countersigned by the Transfer Agent and Registered by the Registrar. in Witness Whereof, the Facsimile Signatures of the Corporation’s Duly Authorized Officers. Dated: Treasurer President and Vice Chairman Countersigned and Registered: American Stock Transfer & Trust Company, LLC (Brooklyn, Ny) Transfer Agent and Registrar by Authorized Signature 21st Century Oncology Holdings, Inc

from 10-Q 10 pages Ninth Supplemental Indenture

from 10-Q 7 pages Eighth Supplemental Indenture, Dated as of August 22, 2013 (This “Supplemental Indenture”), Among Radiation Therapy Services, Inc., a Florida Corporation (The “Company,” Which Term Includes Its Successors and Assigns), Each Other Then Existing Guarantor Under the Indenture Referred to Below (The “Guarantors”), and Wells Fargo Bank, National Association, as Trustee (“The Trustee”) Under the Indenture Referred to Below

from 10-Q 10 pages First Supplemental Indenture

from 8-K 171 pages Oncure Holdings, Inc. $82,500,000 11¾% Senior Secured Notes Due 2017 Amended and Restated Indenture Dated as of October 25, 2013 Wilmington Trust, National Association, as Trustee and Collateral Agent

from 10-Q 9 pages Seventh Supplemental Indenture

from 8-K 28 pages Registration Rights Agreement by and Among Radiation Therapy Services, Inc. Guarantors Listed on Schedule I Hereto and Wells Fargo Securities, LLC Morgan Stanley & Co. LLC Suntrust Robinson Humphrey, Inc. Dated as of May 10, 2012 Registration Rights Agreement

from 8-K 132 pages Radiation Therapy Services, Inc. $350,000,000 87/8% Senior Secured Second Lien Notes Due 2017 Indenture Dated as of May 10, 2012 Wilmington Trust, National Association, as Trustee and Collateral Agent