Dermira, Inc. Watch

from 8-K 7 pages Recitals

from S-3 34 pages Dermira, Inc. and , as Trustee Indenture Dated as of ,

from S-3 5 pages Form of Debt Security

from 8-K 98 pages Dermira, Inc. and U.S. Bank National Association, as Trustee Indenture Dated as of May 16, 2017 3.00% Convertible Senior Notes Due 2022

from S-3 34 pages Dermira, Inc. and , as Trustee Indenture Dated as of ,

from S-3 5 pages Form of Debt Security

from S-1 32 pages Amended and Restated Investors’ Rights Agreement

from S-1 2 pages Dm Incorporated Under the Laws of the State of Delaware This Certifies That Cusip 24983l 10 4 See Reverse for Certain Definitions Is the Record Holder of Fully Paid and Nonassessable Shares of Common Stock, $0.001 Par Value, of Dermira, Inc. Transferable on the Books of the Corporation in Person or by Duly Authorized Attorney Upon Surrender of This Certificate Properly Endorsed. This Certificate Is Not Valid Until Countersigned by the Transfer Agent and Registered by the Registrar. Witness the Facsimile Seal of the Corporation and the Facsimile Signatures of Its Duly Authorized Officers. Dated: President Secretary Delaware Seal Dermira, Inc. Corporate August 18, 2010 Countersigned and Registered: American Stock Transfer & Trust Company, LLC (New York, Ny) Transfer Agent and Registrar By: Authorized Signature

from DRS 32 pages Amended and Restated Investors’ Rights Agreement