MoonLake Immunotherapeutics Watch

from S-1/A 5 pages Certain Personally Identifiable Information Contained in This Document, Marked by Brackets as [***], Has Been Omitted From This Exhibit Pursuant to Item 601(a)(6) Under Regulation S-K. Amendment to the Loan Agreement Dated as of October 15, 2021, as Amended 1. Biotechnology Value Fund, L.P. 44 Montgomery Street, 40th Floor San Francisco, Ca 94104, USA [***] (Hereinafter “Lender 1”) 2. Biotechnology Value Fund II, L.P. 44 Montgomery Street, 40th Floor San Francisco, Ca 94104, USA [***] (Hereinafter “Lender 2”) 3. Biotechnology Value Trading Fund Os, L.P. Po Box 309 Ugland House, Grand Cayman Ky1-1104, Cayman Islands [***] (Hereinafter “Lender 3”) (Each a “Lender” and Collectively the “Lenders”) and 4. Moonlake Immunotherapeutics AG Dorfstrasse 29 6300 Zug, Switzerland [***] (Hereinafter the “Borrower”) (The Lenders, the Borrower Each a “Party” and Collectively the “Parties”) Amendment to the Loan Agreement Dated as of October 15, 2021, as Amended

from S-1/A 5 pages Certain Personally Identifiable Information Contained in This Document, Marked by Brackets as [***], Has Been Omitted From This Exhibit Pursuant to Item 601(a)(6) Under Regulation S-K. Amendment to the Loan Agreement Dated as of October 15, 2021 1. Biotechnology Value Fund, L.P. 44 Montgomery Street, 40th Floor San Francisco, Ca 94104, USA [***] (Hereinafter “Lender 1”) 2. Biotechnology Value Fund II, L.P. 44 Montgomery Street, 40th Floor San Francisco, Ca 94104, USA [***] (Hereinafter “Lender 2”) 3. Biotechnology Value Trading Fund Os, L.P. Po Box 309 Ugland House, Grand Cayman Ky1-1104, Cayman Islands [***] (Hereinafter “Lender 3”) (Each a “Lender” and Collectively the “Lenders”) and 4. Moonlake Immunotherapeutics AG Dorfstrasse 29 6300 Zug, Switzerland [***] (Hereinafter the “Borrower”) (The Lenders, the Borrower Each a “Party” and Collectively the “Parties”) Amendment to the Loan Agreement Dated as of October 15, 2021

from S-1/A 15 pages Certain Personally Identifiable Information Contained in This Document, Marked by Brackets as [***], Has Been Omitted From This Exhibit Pursuant to Item 601(a)(6) Under Regulation S-K. Loan Agreement 1. Biotechnology Value Fund, L.P. 44 Montgomery Street, 40th Floor San Francisco, Ca 94104, USA [***] (Hereinafter “Lender 1”) 2. Biotechnology Value Fund II, L.P. 44 Montgomery Street, 40th Floor San Francisco, Ca 94104, USA [***] (Hereinafter “Lender 2”) 3. Biotechnology Value Trading Fund Os, L.P. Po Box 309 Ugland House, Grand Cayman Ky1-1104, Cayman Islands [***] (Hereinafter “Lender 3”) 4. Moonlake Immunotherapeutics AG C/O Kd Zug-Treuhand AG Untermüli 7 6302 Zug, Switzerland [***]

from 8-K 22 pages Loan Agreement Preamble A. the Borrower Is Organized in the Form of a Swiss Stock Corporation (Aktiengesellschaft) Registered With the Commercial Register of the Canton of Zug Under the Number Che-433.093.536

from DEFA14A 22 pages Loan Agreement Preamble A. the Borrower Is Organized in the Form of a Swiss Stock Corporation (Aktiengesellschaft) Registered With the Commercial Register of the Canton of Zug Under the Number Che-433.093.536