Tripos Inc Watch

from 8-K 20 pages Amended and Restated Stock Purchase and Sale Agreement by and Among Tripos, Inc., a Utah Corporation, Tripos Uk Holdings Limited, a Private Limited Company Incorporated in England, and Commonwealth Biotechnologies, Inc., a Virginia Corporation Dated as of June 6, 2007

from 8-K 3 pages This Deed of Release Is Made the 4th Day of June Two Thousand and Seven Between: (1) the Secretary of State for Trade and Industry Whose Principal Office Is at 1 Victoria Street, London Sw1h 0et (“The Secretary of State”); (2) Tripos Discovery Research Limited (Formerly Tripos Receptor Research Limited) a Company Incorporated in England and Wales With Company Number 02493812 Whose Registered Office Is Situated at the Courtyard, High Street, Ascot, Berkshire Sl5 7hp (“Tripos Discovery”); and (3) Tripos Inc a Company Incorporated in Utah Whose Registered Office Is Situated at 1699 South Hanley Road, St. Louis, Missouri 63144, USA (“Tripos Inc”) Whereas:- (A) by Grant Offer Letter (“The Grant Letter”) Dated 23rd April 2002 the Secretary of State Offered, and the Tripos Discovery Accepted, a Grant Not Exceeding £2,400,000 to Carry Out the Project Therein Described

from 8-K 8 pages Supplemental Agreement Relating to the Sale of Land and Building at Bude Stratton Industrial Estate WWW.ASHFORDS.CO.UK 1

from 8-K 5 pages Amendment and Waiver Agreement

from 8-K 23 pages Registration Rights Agreement This Registration Rights Agreement (This "Agreement") Is Made and Entered Into as of May 4, 2006, by and Between Tripos, Inc., a Utah Corporation (The "Company"), and the Investors Signatory Hereto (Each an "Investor" and Collectively, the "Investors"). This Agreement Is Made Pursuant to the Securities Purchase Agreement, Dated as of the Date Hereof, Between the Company and the Investors (The "Purchase Agreement"). the Company and the Investors Hereby Agree as Follows: 1. Definitions. Capitalized Terms Used and Not Otherwise Defined Herein That Are Defined in the Purchase Agreement Shall Have the Meanings Given Such Terms in the Purchase Agreement. as Used in This Agreement, the Following Terms Shall Have the Meanings Set Forth in This Section 1: "Common Stock" Means the Company's Common Stock, Par Value $.01 Per Share. "Effective Date" Means, With Respect to Any Registration Statement, the Date That the Commission First Declares Effective Such Registration Statement

from 8-K 12 pages Warrant to Subscribe for Shares Stock Purchase Warrant to Subscribe for and Purchase Stock of Tripos, Inc

from 8-K 29 pages 1.1 Definitions. in Addition to the Terms Defined Elsewhere in This Agreement, for All Purposes of This Agreement, the Following Terms Shall Have the Meanings Indicated in This Section 1.1

from S-1/A ~5 pages Tripos, Inc. 2005 Equty Incentive Plan Stock Option Agreement

from S-1/A ~5 pages Tripos, Inc. 1994 Director Option Plan Stock Option Agreement

from S-1/A ~5 pages Tripos, Inc. 1994 Stock Plan Stock Option Agreement

from S-1/A ~5 pages Tripos, Inc. Indemnification Agreement

from S-1/A ~5 pages Executive Severance Agreement This Executive Severance Agreement

from S-1/A ~5 pages December 21, 2004 Mr. James Rubin Senior Vice President and Chief Financial Officer Tripos Inc. 1699 South Hanley Road St. Louis, Mo 63144 Dear Mr. Rubin