Shire Plc Watch

from 8-K 6 pages Consent Request US$2,100,000,000 Multicurrency Revolving and Swingline Facilities Agreement Dated 12 December 2014

from 8-K 254 pages Shire Plc as the Company Abbey National Treasury Services PLC (Trading as Santander Global Banking and Markets) Bank of America Merrill Lynch International Limited Barclays Bank PLC Citigroup Global Markets Limited Lloyds Bank PLC the Royal Bank of Scotland PLC Sumitomo Mitsui Banking Corporation as Mandated Lead Arrangers and Bookrunners Dnb Bank Asa the Bank of Tokyo-Mitsubishi Ufj, Ltd. Credit Suisse AG, London Branch Deutsche Bank Luxembourg S.A. Goldman Sachs Bank USA Mizuho Bank, Ltd. Morgan Stanley Bank International Limited as Arrangers With Barclays Bank PLC as Facility Agent, Euro Swingline Agent and Dollar Swingline Agent US$ 2,100,000,000 Multicurrency Revolving and Swingline Facilities Agreement Dated 12 December 2014 Slaughter and May One Bunhill Row London Ec1y 8yy (Mjd/Vbg) 525001968 1 Contents

from 425 103 pages Amendment No. 1 to 364-Day Bridge Credit Agreement August 11, 2014

from 425 113 pages $4,000,000,000 Revolving Credit Agreement Dated as of August 18, 2014 Among Abbvie Inc. and Abbvie Private Limited, as Borrowers, the Guarantor Party Hereto, Various Financial Institutions, as Lenders, and Jpmorgan Chase Bank, N.A. as Administrative Agent Bank of America, N.A. and Morgan Stanley Senior Funding, Inc. as Syndication Agents Barclays Bank PLC Bnp Paribas Deutsche Bank Securities Inc. Hsbc Bank USA, N.A. and Société Générale, as Documentation Agents J.P. Morgan Securities LLC, Merrill Lynch, Pierce, Fenner & Smith Incorporated and Morgan Stanley Senior Funding, Inc. as Joint Lead Arrangers and Bookrunners

from 425 111 pages £3,200,000,000 Term Loan Credit Agreement Dated as of August 18, 2014 Among Abbvie Holdings Private Limited, as Borrower, the Guarantors Party Hereto, Various Financial Institutions, as Lenders, and Jpmorgan Chase Bank, N.A. as Administrative Agent Bank of America, N.A., as Syndication Agent Barclays Bank PLC Bnp Paribas Hsbc Bank USA, N.A. and Société Générale, as Documentation Agents J.P. Morgan Securities LLC and Merrill Lynch, Pierce, Fenner & Smith Incorporated, as Joint Lead Arrangers and Bookrunners

from 425 99 pages £13,500,000,000 364-Day Bridge Credit Agreement Dated as of July 17, 2014 Among Abbvie Private Limited, as Borrower, the Guarantors Party Hereto, Various Financial Institutions, as Lenders, and Jpmorgan Chase Bank, N.A. as Administrative Agent J.P. Morgan Securities LLC, as Sole Arranger and Bookrunner

from 10-K 211 pages Shire Plc as the Company Abbey National Treasury Services PLC (Trading as Santander Global Banking and Markets) Banc of America Securities Limited Barclays Capital Citigroup Global Markets Limited Lloyds Tsb Bank PLC the Royal Bank of Scotland PLC as Mandated Lead Arrangers and Bookrunners Credit Suisse AG, London Branch Deutsche Bank AG, London Branch Goldman Sachs International Morgan Stanley Bank, N.A. Sumitomo Mitsui Banking Corporation, Brussels Branch as Arrangers With Barclays Bank PLC as Facility Agent, Euro Swingline Agent and Dollar Swingline Agent US$ 1,200,000,000 Multicurrency Revolving and Swingline Facilities Agreement Dated 23 November 2010 Slaughter and May One Bunhill Row London Ec1y 8yy (Rel/Kyh) 506171078_4.doc Contents

from 10-Q >50 pages US$800,000,000 Facilities Agreement Dated 15 June 2005 for Shire Pharmaceuticals Group PLC Arranged by Abn Amro Bank N.V. Barclays Capital Citigroup Global Markets Limited Hsbc Bank PLC the Royal Bank of Scotland PLC With Hsbc Bank PLC Acting as Facility Agent Hsbc Bank PLC Acting as Euro Swingline Agent Hsbc Bank USA, National Association Acting as Dollar Swingline Agent Multicurrency Revolving Facilities Agreement Contents

from F-4/A >50 pages Amended and Re-Stated Credit Agreement